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左乙拉西坦联合丙戊酸钠治疗儿童癫痫的临床效果

李叶广 张娜娜 王洪琰

妇儿健康导刊2024,Vol.3Issue(1):114-116,120,4.
妇儿健康导刊2024,Vol.3Issue(1):114-116,120,4.

左乙拉西坦联合丙戊酸钠治疗儿童癫痫的临床效果

Clinical effect of Levetiracetam combined with Sodium Valproate in the treatment of epilepsy in children

李叶广 1张娜娜 2王洪琰1

作者信息

  • 1. 山东省菏泽市单县东大医院儿科,山东菏泽 274300
  • 2. 山东省菏泽市单县中心医院检验科,山东菏泽 274300
  • 折叠

摘要

Abstract

Objective To explore the clinical effect of Levetiracetam combined with Sodium Valproate in the treatment of epilepsy in children.Methods A total of 64 children with epilepsy in Shanxian Dongda Hospital of Heze from January 2021 to June 2022 were selected and divided into control group and combination group according to the random number table method,with 32 cases in each group.The control group was treated with Sodium Valproate,and the combination group was treated with Levetiracetam combined with Sodium Valproate.The therapeutic effect of the two groups was compared.Results After treatment,the neurological injury indexes in the combination group were lower than those in the control group(P<0.05),and the cognitive function scores in the combination group were lower than those in the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Levetiracetam combined with sodium valproate treating children with epilepsy has significant clinical effect,which can reduce neurological injury,improve cognitive function,and is worthy of promotion.

关键词

儿童癫痫/左乙拉西坦/丙戊酸钠/神经损伤/认知功能

Key words

Children with epilepsy/Levetiracetam/Sodium Valproate/Neurological injury/Cognitive function

分类

医药卫生

引用本文复制引用

李叶广,张娜娜,王洪琰..左乙拉西坦联合丙戊酸钠治疗儿童癫痫的临床效果[J].妇儿健康导刊,2024,3(1):114-116,120,4.

妇儿健康导刊

2097-115X

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