摘要
Abstract
Objective To analyze the research status and trend of immunotherapy for ovarian cancer by bibliometrics analysis.Methods Using the Web of Science core collection database as data source,CiteSpace 6.2.R4 software and VOSviewer 1.6.18 software were used to take visual analysis on the country,institution,authors,reference and keywords of related literature on immunotherapy for ovarian cancer published between 2006 and 2022.Results A total of 1039 papers were included in the analysis and the annual publication volume was showing an increasing trend year by year,especially in the past three years.The country with the highest number of publication was the United States,followed by China.The institution with the highest number of publication was the University of Texas System.Among the research authors,the highest frequency of appearance was Odunsi Kunle,Coukos George,Kandalaft Lana E and Coleman Robert L.The most frequently cited reference was Safety and Antitumor Activity of Anti-PD-1 Antibody,Nivolumab,in Patients With Platinum-Resistant Ovarian Cancer.Among the keywords,except for"ovarian cancer"and"immunotherapy","tumor microenvironment"and"immune checkpoint inhibitor"had the highest correlation with other keywords.Conclusion Tumor microenvironment and immune checkpoint inhibitor are the current research hotspots of immunotherapy for ovarian cancer.The study of the molecular mechanism of interaction between tumor cells and immune cells in the tumor microenvironment and the research of the effective combination of immunotherapy and other therapies are the research trends in this field.关键词
卵巢癌/免疫治疗/文献计量学/可视化分析Key words
Ovarian cancer/Immunotherapy/Bibliometrics/Visual analysis分类
医药卫生
