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妊娠高血压疾病的多因素logistic回归分析

倪健美 牛秀珑 王晓静 王涛 张芯

武警医学2024,Vol.35Issue(1):56-60,5.
武警医学2024,Vol.35Issue(1):56-60,5.

妊娠高血压疾病的多因素logistic回归分析

Multivariate logistic regression analysis of pregnancy-induced hypertension

倪健美 1牛秀珑 2王晓静 3王涛 3张芯3

作者信息

  • 1. 300199,天津市中西医结合医院
  • 2. 300162 天津,武警特色医学中心高原高寒环境及心血管病防治研究所
  • 3. 300162 天津,武警特色医学中心高原高寒环境及心血管病防治研究所||300162,天津市心血管重塑与靶器官损伤重点实验室
  • 折叠

摘要

Abstract

Objective To analyze the risk factors of pregnancy-induced hypertension and provide evidence support for its pre-vention.Methods A total of 3747 pregnant women with pregnancy outcomes were randomly selected from a cohort of pregnant women in Dongli District,Hedong District and Hebei District of Tianjin from January 2016 to December 2017.Three hundred and nine pa-tients with gestational hypertension were selected as the observation group,and the remaining 3438 cases were regarded as the control group for statistical analysis.Single factor logistic analysis was conducted on potential influencing factors.Considering the possible in-teraction among all factors,a multi-factor logistic model was further used for analysis.Finally,a univariate analysis was conducted to investigate the severe adverse outcomes of pregnancy-induced hypertension and the developmental status of newborns within 42 days of birth.Results Single factor logistic analysis showed that gestational hypertension was related to age,body mass index at initial exami-nation,family history of hypertension,hypertension,and high-risk conditions during pregnancy,such as assisted reproductive technol-ogy,diabetes during pregnancy,and abnormal serum free thyroid hormone,etc.Multivariate logistic analysis showed that initial BMI(OR=1.172,95%CI:1.138-1.207),family history of hypertension(OR=6.599,95%CI:3.670-11.865),history of hypertension(OR=7.415,95%CI:3.431-16.027),and assisted reproductive technology(OR=3.406,95%CI:1.767-6.566)were risk factors for gestational hypertension.Through univariate analysis,it was found that gestational hypertension had an impact on delivery mode,gesta-tional week,postpartum blood pressure at 42 days,birth weight,length and weight of newborns at 42 days.Conclusions Early preven-tion measures should be carried for pregnant women with high initial BMI,family history of hypertension,history of hypertension,and pregnancy with assisted reproductive technology,so as to reduce the impact on delivery methods,gestational weeks,postpartum blood pressure at 42 days and neonatal development.

关键词

妊娠高血压/广义线性回归模型/危险因素

Key words

pregnancy-induced hypertension/generalized linear regression model/risk factor

分类

医药卫生

引用本文复制引用

倪健美,牛秀珑,王晓静,王涛,张芯..妊娠高血压疾病的多因素logistic回归分析[J].武警医学,2024,35(1):56-60,5.

基金项目

天津市科技计划项目(15ZXJZSY00010) (15ZXJZSY00010)

武警医学

OACSTPCD

1004-3594

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