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超声在克罗恩病靶向治疗早期疗效评估中的应用OACSTPCD

Early Efficacy Assessment of Targeted Therapy for Crohn's Disease by Ultrasound

中文摘要英文摘要

克罗恩病(Crohn's disease,CD)是一种发病机制复杂的慢性炎症性肠病.近年来,靶向治疗的广泛应用显著改善了CD患者的预后.若能在靶向治疗早期进行疗效评估,将有利于筛选出治疗获益的患者,同时可对治疗无效的患者及时调整治疗方案.超声在CD活动性评估、疗效评价方面具有准确性高、无电离辐射、患者接纳程度高的优势,在CD早期疗效评估方面具有潜在临床应用价值.本文就超声在CD靶向治疗早期疗效评估中的应用进行综述,以期为优化CD患者的治疗方案提供借鉴.

Crohn's disease(CD)is a chronic inflammatory bowel disease with complicated patho-genesis and prolonged condition.In recent years,with the development of targeted therapy,biological a-gents have been widely used in the treatment of CD,which has significantly improved the prognosis of CD patients.If the efficacy evaluation can be carried out at the early stage of targeted therapy,it may help to figure out the patients who can benefit from the treatment and optimize the treatment plan for the ineffective patients in time.In the evaluation of CD activity and efficacy,ultrasound has the advantages of high accu-racy,no radiation and high patient acceptance,and therefore has potential clinical application value in the early efficacy evaluation of CD targeted therapy.This article reviews the research progress to provides a ref-erence for optimizing the treatment plan for CD patients.

秦菁;朱庆莉

中国医学科学院北京协和医学院, 北京 100730||中国医学科学院北京协和医院超声医学科, 北京 100730中国医学科学院北京协和医院超声医学科, 北京 100730

临床医学

超声早期疗效克罗恩病靶向治疗

ultrasonographyearly efficacyCrohn's diseasetargeted therapy

《协和医学杂志》 2024 (001)

130-134 / 5

National High-Level Hospital Clinical Research Funding(2022-PUMCH-C-018);National Natural Science Foundation of China(81791640) 中央高水平医院临床科研专项(2022-PUMCH-C-018);国家自然科学基金(81791640)

10.12290/xhyxzz.2023-0306

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