结直肠癌组织miR-330-5p、PTBP1的表达与病理参数和预后的关系OACSTPCD
The expression of miR-330-5p and PTBP1 in colorectal cancer tissue and their relationship with pathological parame-ters and prognosis
目的 分析结直肠癌组织微小核糖核酸-330-5p(miR-330-5p)、多聚嘧啶区结合蛋白 1(PTBP1)的表达与病理参数及预后的关系.方法 选取2018 年1 月—2020 年 5 月南通市中医院肛肠科收治的结直肠癌患者 101例,收集术中部分癌组织及其癌旁组织,采用实时荧光定量聚合酶链式反应检测miR-330-5p、PTBP1 mRNA表达.通过Targetscan数据库预测miR-330-5p与PTBP1 的结合位点,分析miR-330…查看全部>>
Objective To analyze the expression of microribonucleic acid-330-5p(miR-330-5p)and polypyrimidine region binding protein 1(PTBP1)in colorectal cancer tissue and their relationship with pathological parameters and progno-sis.Methods One hundred and one patients with colorectal cancer admitted to the Anorectal Department of Nantong Tra-ditional Chinese Medicine Hospital from January 2018 to May 2020 were selected.Part of the cancer tissue and its adjacent tiss…查看全部>>
周钰杰;杨芳;严晶;钱政;马鸿旭
226001 江苏省南通市中医院肛肠科226001 江苏省南通市中医院消化内科210023 南通,南京中医药大学第一临床医学院226001 江苏省南通市中医院肛肠科226001 江苏省南通市中医院肛肠科
临床医学
结直肠癌微小核糖核酸-330-5p多聚嘧啶区结合蛋白1病理参数预后
Colorectal cancerMicroRNA-330-5pPolypyrimidine tract binding protein 1Pathological parametersPrognosis
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68-72,5
国家自然科学基金资助项目(81503536) National Natural Science Foundation of China(81503536)
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