云南化工2024，Vol.51Issue(1)：30-33,37,5.DOI:10.3969/j.issn.1004-275X.2024.01.07
矢车菊素半合成方法实验教学实践
Comprehensive Experiments in Organic Chemistry:A Semi-Synthetic Method for Cyanidin
摘要
Abstract
In this experiment,quercetin was used as the starting substrate to synthesize cyanidin,a natural active ingredient,under room tem-perature through hydroxyl groups protection,carbonyl reduction,and deprotection by acidification.The intermediate and final product were characterized by TLC,UV,HPLC-MS,and IR.The experimental principle is simple and the operation is convenient for college students.The maximum absorption wavelength of the substrate and product are significantly different.The color change is obvious,and the final yield is 51.74%.Cyanidin is widely used in food industry.Therefore,the preparation of cyanidin through synthetic method can effectively guide students to apply organic chemistry theory into practice,stimulate students'interest,and improve experimental skills.关键词
有机化学实验/羟基保护/酸化脱保护/矢车菊素/综合实验Key words
organic chemistry experiment/hydroxyl group protection/deprotection by acidification/cyanidin/comprehensive experiment分类
教育学引用本文复制引用
侯婷婷,刘渝钶,杨胜男,孙萌萌,胡海鹏,王广途,王晗光,吴贺君,蒲祥..矢车菊素半合成方法实验教学实践[J].云南化工,2024,51(1):30-33,37,5.基金项目
四川省教育厅教改项目(JG2018-352,JG2021-484) （JG2018-352,JG2021-484）
四川农业大学双带头人教师党支部书记工作室(蒲祥) （蒲祥）
四川农业大学教改项目(X201935,X202138). （X201935,X202138）
