微创医学2023，Vol.18Issue(6)：689-693,5.DOI:10.11864/j.issn.1673.2023.06.05
射频消融术联合超声雾化治疗儿童腺样体肥大的临床研究
Clinical study of radiofrequency ablation combined with ultrasonic gas-atomization in the treatment of adenoid hypertrophy in children
摘要
Abstract
Objective To investigate the clinical efficacy of radiofrequency ablation combined with ultrasonic gas-atomization in the treatment of adenoid hypertrophy in children.Methods A total of 78 children with adenoid hypertrophy were selected as research objects and divided into conventional group(n=39)and combination group(n=39)by the random number table method.The conventional group was treated with radiofrequency ablation alone,and the combination group was treated with radiofrequency ablation combined with budesonide+chymotrypsin ultrasonic gas-atomization.The clinical efficacy,occurrence of adverse reactions,symptom score and serum inflammatory index level were compared between the two groups.Results The clinical efficacy of the combination group was better than that of the conventional group,with statistically significant difference(P＜0.05).Before treatment,there were no statistically significant differences in snoring,nasal obstruction,mouth breathing and apnea symptom scores between the two groups(all P＞0.05).After treatment,the scores of symptoms in both groups were significantly reduced,and those of the combination group were lower than those of the conventional group,with statistically significant differences(all P＜0.05).The total incidence of adverse reactions in the combination group was significantly lower than that in the conventional group,and the difference was statistically significant(P＜0.05).Before treatment,there were no significant differences in serum levels of C-reactive protein(CRP),tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)between the two groups(all P＞0.05).After treatment,the levels of serum CRP,TNF-α and IL-6 in the two groups were significantly decreased,and those in the combination group were lower than those in the conventional group,with statistically significant differences(all P＜0.05).Conclusion Radiofrequency ablation combined with ultrasonic gas-atomization in the treatment of adenoid hypertrophy in children has significant clinical efficacy,effectively promoting the regression of inflammation,reducing the symptoms of adenoid hypertrophy in children,and reducing the risk of adverse reactions,which is worthy of clinical promotion and application.关键词
射频消融术/超声雾化/儿童/腺样体肥大/疗效Key words
Radiofrequency ablation/Ultrasonic gas-atomization/Children/Adenoid hypertrophy/Efficacy分类
医药卫生引用本文复制引用
谢婷,黄惠玲,朱友莲..射频消融术联合超声雾化治疗儿童腺样体肥大的临床研究[J].微创医学,2023,18(6):689-693,5.基金项目
赣州市指导性科技计划项目(编号:GZ2020ZSF328) （编号:GZ2020ZSF328）
