空军军医大学学报2024，Vol.45Issue(1)：22-25,4.DOI:10.13276/j.issn.2097-1656.2024.01.005
巴马香猪原位肾脏移植模型的建立及手术方式效果对比
Establishment of orthotopic kidney transplantation model and comparison of different vascular anastomosis methods in Bama Xiang pigs
摘要
Abstract
Objective To establish porcine orthotopic kidney transplantation model and investigate the effect and complication rate of different vascular anastomosis methods.Methods The kidney was obtained by whole donor nephrectomy.After kidney repairment of the transplanted kidney,orthotopic kidney transplantation was performed with end-to-end anastomosis between the arteries/veins of the transplanted kidney and the arteries/veins of the recipient pigs.According to different vascular anastomosis methods,the recipient pigs were divided into traditional anastomosis group(n=12)and micro-anastomosis group(n=12).Arterial anastomosis time,venous anastomosis time,total operation time,renal warm ischemia time,renal cold ischemia time and incidence of vascular complications were compared between the two groups.Results Arterial anastomosis time,venous anastomosis time,total operation time and renal cold ischemia time in the traditional anastomosis group were lower than those in the micro-anastomosis group,and the incidence of vascular complications in the traditional anastomosis group was higher than that in the micro-anastomosis group.Conclusion Porcine orthotopic kidney transplantation model has strong operability and renal arteriovenous micro-anastomosis can reduce vascular complications of transplanted kidney.关键词
原位肾移植/血管吻合/移植效果/模型建立Key words
orthotopic kidney transplantation/vascular anastomosis/transplantation effect/model establishment分类
医药卫生引用本文复制引用
韩士超,秦卫军,马帅军,戚若晨,王国辉,张小燕,刘克普,范效铮,魏迪,杨晓剑..巴马香猪原位肾脏移植模型的建立及手术方式效果对比[J].空军军医大学学报,2024,45(1):22-25,4.基金项目
国家自然科学基金(82102322) （82102322）
