空军军医大学学报2024,Vol.45Issue(1):106-110,5.DOI:10.13276/j.issn.2097-1656.2024.01.022
关于多灶性肝癌诊疗的思考
Reflections on the diagnosis and treatment of multifocal hepatocellular carcinoma
摘要
Abstract
Multifocal hepatocellular carcinoma(HCC)has a high incidence in HCC,which is characterized by high invasiveness and high proliferation,and is closely related to poor prognosis of patients.There are many factors related to the occurrence of multifocal HCC,and the pathogenesis is complex,which is still in the exploratory research stage.The study of multifocal HCC substaging has achieved certain results,but it is controversial in clinical practice due to the limitations of its treatment options.More and more studies suggest that liver resection for multifocal HCC is an effective treatment,with better long-term prognosis and lower recurrence rate and mortality.However,it is very important to select surgery suitable for patients.For patients with multifocal HCC who cannot be treated with surgical resection in one stage,the most appropriate combination therapy should be selected according to their different manifestations.Therefore,a more complete evaluation model is needed in clinical practice to conduct stratified research for patients with multifocal HCC and achieve precise treatment to benefit more patients.关键词
肝癌,多灶性/发生机制/临床分期/手术切除/经皮肝动脉灌注化疗栓塞术/射频消融术/免疫治疗Key words
hepatocellular carcinoma,multifocal/pathogenesis/clinical stage/surgical resection/transarterial chemoembolization/radio frequency ablation/immunotherapy分类
医药卫生引用本文复制引用
张小晶,金亮,陶开山,王琳..关于多灶性肝癌诊疗的思考[J].空军军医大学学报,2024,45(1):106-110,5.基金项目
国家自然科学基金面上项目(81770560) (81770560)