摘要
Abstract
Objective To analyze the correlation between peripheral blood procalcitonin(PCT),platelet to lymphocyte ratio(PLR)and the severity of acute pancreatitis,and the predictive value of PCT and PLR for poor prognosis of acute pancreatitis.Methods A total of 112 patients with acute pancreatitis who were admitted to Xiangcheng People's Hospital from January 2018 to June 2022 were selected.The levels of peripheral blood PCT were measured and PLR was calculated 24 hours after admission.According to the severity of the patients,they were divided into good prognosis group and poor prognosis group.The predictive value of peripheral blood PCT and PLR levels for patients with poor prognosis of acute pancreatitis was analyzed by receiver operating characteristic(ROC)curve.Results Among the 112 patients with acute pancreatitis,there were 22 cases(19.64%)in the poor prognosis group and 90 cases(80.36%)in the good prognosis group.There was no significant difference in general data,serum creatinine(CREA),blood calcium,and peripheral blood leukocytes between the two groups(P＞0.05).The levels of peripheral blood PCT and PLR in the poor prognosis group were significantly higher than those in the good prognosis group,and the difference was statistically significant(P＜0.05).High expression levels of peripheral blood PCT and PLR were both related factors for patients with poor prognosis of acute pancreatitis,and the difference was statistically significant(P＜0.05).ROC analysis showed that the sensitivity of ROC prediction for patients with poor prognosis of acute pancreatitis by single and combined peripheral blood PCT and PLR levels were 62.54%,70.85%,and 89.85%respectively,and the specificity were 75.89%,74.69%,and 72.58%respectively.The area under the curve(AUC)were 0.785,0.796,and 0.889 respectively.The predictive efficacy of single peripheral blood PCT and PLR levels for patients with poor prognosis of acute pancreatitis was lower than that of the combination,and the difference was statistically significant(P＜0.05).Conclusion Patients with poor prognosis of acute pancreatitis have higher expression levels of peripheral blood PCT and PLR.Both peripheral blood PCT and PLR levels have certain clinical predictive efficacy for patients with poor prognosis of acute pancreatitis.关键词
急性胰腺炎/降钙素原/血小板与淋巴细胞比值/严重程度Key words
Acute Pancreatitis/Procalcitonin/Platelet to Lymphocyte Ratio/Severity分类
医药卫生
