中风与神经疾病杂志2024，Vol.41Issue(1)：47-51,5.DOI:10.19845/j.cnki.zfysjjbzz.2024.0009
DNA甲基化/去甲基化调控缺血性卒中的研究进展
Research advances in DNA methylation/demethylation in regulating ischemic stroke
摘要
Abstract
Stroke is the leading cause of death and disability in China.Ischemic stroke(IS)is the dominantsubtype of stroke with a proportion more than 80%.Certainly,IS is a complex disease with a ge-neticpredisposition.DNA methylation/demethylation is a crucial epigenetic mechanism,which has been found to play an important role in the pathogenesis and recurrence of IS in recent years,indicating that DNA methylation/demethylation may be potential diagnostic biomarker and therapeutic targets for IS.The latest advances of DNA methylation/demethylation in IS is summarized as follows.关键词
缺血性卒中/表观遗传学/DNA甲基化/DNA去甲基化Key words
Ischemic stroke/Epigenetics/DNA methylation/DNA demethylation分类
医药卫生引用本文复制引用
李亚楠,韩非原,王文,伍昊文,孙宏巍..DNA甲基化/去甲基化调控缺血性卒中的研究进展[J].中风与神经疾病杂志,2024,41(1):47-51,5.基金项目
哈尔滨医科大学附属第一医院科研创新基金(2020B05) （2020B05）
黑龙江省级大学生创新创业项目(S202210226012) （S202210226012）
