中风与神经疾病杂志2024，Vol.41Issue(1)：58-62,5.DOI:10.19845/j.cnki.zfysjjbzz.2024.0011
中老年高血压病患者中重度脑白质高信号列线图模型的构建
Construction of a nomogram model for predicting moderate-to-severe white matter hyperintensity in middle-aged and elderly patients with hypertension
摘要
Abstract
Objective To investigate the influencing factors for white matter hyperintensity(WMH)in middle-aged and elderly patients with hypertension,and to establish and verity a nomogram prediction model.Methods A total of 198 middle-aged and elderly patients with hypertension and WMH who were hospitalized in our hospital from January 2022 to April 2023 were enrolled.Related clinical data were analyzed,and related data were recorded.A binary logistic regression analysis was used to investigate the independent risk factors for WMH and establish a nomogram,and the re-ceiver operating characteristic(ROC)curve and the calibration curve were used to evaluate the diagnostic efficacy of the nomogram.Results Age,course of hypertension,cystatin C,homocysteine,red blood cell distribution width,and cognitive impairment were the independent influencing factors for WMH in the middle-aged and elderly patients with hypertension.The nomogram established showed good diagnostic efficacy(AUC=0.815,95%CI 0.756～0.874,P<0.001)and calibration ability(C index=0.794).Conclusion The nomogram established in this study has a good predictive ability for moderate-to-severe WMH in middle-aged and elderly patients with hypertension and can provide certain help for clinical workers.关键词
脑白质高信号/MRI/列线图/影响因素Key words
White matter hyperintensity/Magnetic resonance imaging/Nomogram/Influencing factor分类
医药卫生引用本文复制引用
徐瑞辰,赵峰,鄢潞潞,郭炫汐,林子贺,庞华军..中老年高血压病患者中重度脑白质高信号列线图模型的构建[J].中风与神经疾病杂志,2024,41(1):58-62,5.基金项目
新疆石河子市科技计划项目(2022NY05) （2022NY05）
