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缺血性脑卒中的侧支循环建立及治疗的研究现状

孙锦 郭莉琛 王萌 苏琳琳 袁庆 胡利民

中国临床药理学杂志2024,Vol.40Issue(2):279-283,5.
中国临床药理学杂志2024,Vol.40Issue(2):279-283,5.DOI:10.13699/j.cnki.1001-6821.2024.02.027

缺血性脑卒中的侧支循环建立及治疗的研究现状

Research status on establishment of collateral circulation and therapy in ischemic stroke

孙锦 1郭莉琛 1王萌 1苏琳琳 1袁庆 1胡利民1

作者信息

  • 1. 天津中医药大学组分中药国家重点实验室、方剂学教育部重点实验室、天津市中药药理学重点实验室,天津 301617
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摘要

Abstract

Intravenous thrombolysis and revascularisation are subject to strict time windows,and most patients still need to reperfuse ischaemic tissue through their own compensatory mechanisms due to subsequent re-occlusion or"no-reflow".A good collateral circulation can prolong the therapeutic window,increase the tolerance of brain tissue to ischaemia and hypoxia,and improve the prognosis,so promoting the establishment of collateral circulation to improve ischaemic tissue perfusion is a new idea in the treatment of ischaemic stroke.In this paper,we provides a review of relevant studies on methods of assessment of collateral circulation,therapeutic approaches,and clinical significance to provide guidance for the treatment of ischaemic stroke.

关键词

缺血性脑卒中/侧支循环/临床意义/治疗方法

Key words

ischemic stroke/collateral circulation/clinical significance/treatment

分类

医药卫生

引用本文复制引用

孙锦,郭莉琛,王萌,苏琳琳,袁庆,胡利民..缺血性脑卒中的侧支循环建立及治疗的研究现状[J].中国临床药理学杂志,2024,40(2):279-283,5.

基金项目

国家自然科学基金资助项目(81573644) (81573644)

天津市自然科学基金资助项目(21JCYBJC01260) (21JCYBJC01260)

中国临床药理学杂志

OA北大核心CSTPCD

1001-6821

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