鼻咽癌去神经肌肉病变的MRI表现OACSTPCD

Objective:To observe the MRI manifestations of denervated muscular lesions(DML)in patients with nasopha-ryngeal carcinoma.Methods:The clinical data and MRI images of DML in 12 patients with nasopharyngeal carcinoma were retrospectively analyzed in our hospital from February 2010 to February 2022.The characteristics of MRI signals,lesion en-hancement,and DWI were observed.Results:Among the DML of 12 patients with nasopharyngeal carcinoma,4 cases showed DML in the masticatory muscles innervated by the mandibular branch of the trigeminal nerve and 8 cases showed DML in the lingual muscles innervated by the hypoglossal nerve.Among the 4 cases of DML in the masticatory muscle,2 cases oc-curred DML after secondary radiotherapy for tumor recurrence,and 2 cases developed DML after initial radiotherapy.Among the 8 cases of DML of the tongue muscles,4 cases appeared after the first course of radiotherapy,3 cases occured after sec-ondary radiotherapy,and 1 case emerged at the initial diagnosis.Muscle atrophy was observed in 4 cases of DML,with two cases showing fat replacement signal and high signal on T1WI,while the other two cases showed isointense signal on T1WI and no fat replacement signal was observed.On T2WI,they showed uneven medium high signal and DWI also showed high signal,with mild to moderate enhancement after enhancement.Muscle atrophy was also observed in 8 cases of tongue muscle DML,and fat replacement signals were observed on T1WI.Among them,5 cases showed equal signals on T2WI and DWI,but no significant enhancement was observed after enhancement.Three cases showed high signal on T2WI and DWI,with mild to moderate enhancement after enhancement.Conclusion:Nasopharyngeal cancer with DML of the masticatory or tongue muscles is relatively rare,but its MRI manifestations have certain characteristics.Identifying the signal manifestations of its MRI can help in the early diagnosis of DML and differentiate it from inflammation or tumor infiltration.