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糖皮质激素对免疫细胞调控的研究进展

李佳荣 张纪岩

中国免疫学杂志2024,Vol.40Issue(1):31-36,6.
中国免疫学杂志2024,Vol.40Issue(1):31-36,6.DOI:10.3969/j.issn.1000-484X.2024.01.004

糖皮质激素对免疫细胞调控的研究进展

Research progress on regulation of glucocorticoids on immune cells

李佳荣 1张纪岩2

作者信息

  • 1. 南华大学药学院,南华大学药物药理研究所,衡阳 421001
  • 2. 南华大学药学院,南华大学药物药理研究所,衡阳 421001||军事科学院军事医学研究院军事认知与脑科学研究所,北京 100850
  • 折叠

摘要

Abstract

The immune system is the defender of human health,whose dysregulation is the source of various diseases.Re-duced immune defense and immune surveillance capabilities lead to difficulties in removing pathogens and malignant cells,thus increasing morbidity and mortality risk.Stress is a major factor in the decline of the immune system.In past studies,it has been demon-strated both in animal and humans that stress increases the levels of neuroendocrine hormones in the body,particularly glucocorticoids and catecholamines.Through the action of these stress hormones,stress has a number of detrimental effects on immune function,and this review combs through the progress of research on the regulation of immune cells by glucocorticoids.

关键词

压力/免疫力/糖皮质激素

Key words

Stress/Immunity/Glucocorticoids

分类

医药卫生

引用本文复制引用

李佳荣,张纪岩..糖皮质激素对免疫细胞调控的研究进展[J].中国免疫学杂志,2024,40(1):31-36,6.

中国免疫学杂志

OA北大核心CSTPCD

1000-484X

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