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单核苷酸多态性(SNP)分析在细菌分子分型中的应用

杨富萍 杨向东 于彬彬 高子厚

中国人兽共患病学报2023,Vol.39Issue(12):1196-1201,1210,7.
中国人兽共患病学报2023,Vol.39Issue(12):1196-1201,1210,7.DOI:10.3969/j.issn.1002-2694.2023.00.139

单核苷酸多态性(SNP)分析在细菌分子分型中的应用

Application of single nucleotide polymorphism(SNP)analysis in bacterial molecular typing

杨富萍 1杨向东 2于彬彬 2高子厚1

作者信息

  • 1. 大理大学,大理 671000||云南省地方病防治所,云南省自然疫源性疾病防控技术重点实验室,大理 671000
  • 2. 云南省地方病防治所,云南省自然疫源性疾病防控技术重点实验室,大理 671000
  • 折叠

摘要

Abstract

Single nucleotide polymorphisms(SNPs),third generation molecular genetic markers,have attracted extensive attention because of their importance in research on genetic diseases,gene evolution,adaptation,species,medicine and other fields.SNPs are found in large numbers,with a wide distribution,stable genetics and high throughput.Moreover,SNPs are suitable for rapid and large-scale screening.These genetic markers have been widely used in molecular typing for a variety of bacteria.Herein,the current status of SNP technology is discussed and compared with other typing methods,and its applica-tions in bacterial molecular typing are reviewed.

关键词

SNP/细菌/分子分型

Key words

SNP/bacteria/molecular typing

分类

医药卫生

引用本文复制引用

杨富萍,杨向东,于彬彬,高子厚..单核苷酸多态性(SNP)分析在细菌分子分型中的应用[J].中国人兽共患病学报,2023,39(12):1196-1201,1210,7.

基金项目

国家自然科学基金(No.81660554,No.30960331) (No.81660554,No.30960331)

兴滇英才支持计划(No.YNWR-MY-2018-035)Supported by the National Natural Science Foundation Project(No.81660554,No.30960331)and Support Plan for Talents in Yunnan(No.YNWR-MY-2018-035) (No.YNWR-MY-2018-035)

中国人兽共患病学报

OA北大核心CSCDCSTPCD

1002-2694

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