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啮齿类动物衰老模型研究新进展

李雪婵 韩乐 王雪文 柳立军 吴建军 王晶

中国实验动物学报2023,Vol.31Issue(12):1605-1609,5.
中国实验动物学报2023,Vol.31Issue(12):1605-1609,5.DOI:10.3969/j.issn.1005-4847.2023.12.011

啮齿类动物衰老模型研究新进展

Research progress in aging rodent models

李雪婵 1韩乐 1王雪文 1柳立军 2吴建军 1王晶1

作者信息

  • 1. 甘肃中医药大学公共卫生学院,兰州 730000
  • 2. 兰州大学第一医院生殖医学中心,兰州 730000
  • 折叠

摘要

Abstract

Aging is a process of degenerative change that occurs as a result of time-related accumulation,associated with age-related diseases.Understanding the causes and mechanisms of aging and finding drugs that can effectively delay aging and prevent and cure age-related diseases currently present a great challenge for humans.Aging animal models thus represent an important tool in aging research,and various aging animal models have been created using different aging mechanisms.These different models having specific advantages and disadvantages,making them suitable for different research purposes.This review considers aging rodent models to provide information for aging research.

关键词

衰老模型/啮齿类动物/机制

Key words

aging model/rodents/mechanism

分类

生物科学

引用本文复制引用

李雪婵,韩乐,王雪文,柳立军,吴建军,王晶..啮齿类动物衰老模型研究新进展[J].中国实验动物学报,2023,31(12):1605-1609,5.

基金项目

国家自然科学基金(82060829,81760835),甘肃省陇东生物资源保护利用与生态修复重点实验室开放基金(LDSWZY2002-3). Funded by National Natural Science Foundation of China(82060829,81760835),Foundation of Gansu Key Laboratory of Protection and Utilization for Biological Resources and Ecological Restoration(LDSWZY2002-3). (82060829,81760835)

中国实验动物学报

OA北大核心CSCDCSTPCD

1005-4847

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