中国实验动物学报2023,Vol.31Issue(12):1629-1635,7.DOI:10.3969/j.issn.1005-4847.2023.12.014
模式动物斑马鱼在人乳腺癌疾病研究中的应用进展
Research progress on the application of a zebrafish model in breast cancer research
摘要
Abstract
The zebrafish xenograft model plays an important role in cancer modelling,especially breast cancer xenografts.This model facilitates the real-time observation of tumor cell growth,metastasis,and interactions with the immune system,thus providing novel insights and experimental foundations for breast cancer treatment.Furthermore,the zebrafish xenograft model offers a valuable tool for high-throughput drug screening.This review provides an overview of the contributions of the zebrafish xenograft model to elucidating the mechanisms underlying breast cancer development,and its use in screening anti-tumor drugs and conducting therapeutic research.关键词
斑马鱼/异种移植模型/乳腺癌Key words
zebrafish/xenotransplantation mode/breast cancer分类
生物科学引用本文复制引用
张敏,张晶晶,宁国柱..模式动物斑马鱼在人乳腺癌疾病研究中的应用进展[J].中国实验动物学报,2023,31(12):1629-1635,7.基金项目
湛江市科技发展专项资金(2022A01231). Funded by the Science and Technology Planning Project of Zhanjiang(2022A01231). (2022A01231)