益生菌在新生儿疾病中的应用进展OACSTPCD

Probiotics are a category of live microorganisms that,when consumed in adequate amounts,exert beneficial effects on health.Research has demonstrated their crucial role in regulating the composition of the gut microbiota,enhancing its barrier function,suppressing inflammation,and participating in immune modulation.The digestive and immune systems of newborns are immature,supplementation with probiotics may improve clinical outcomes of necrotizing enterocolitis and pathological jaundice in the newborn.This review aims to elucidate the role of probiotics in assisting the management of neonatal digestive system disorders and systemic diseases.However,the effectiveness and safety of probiotics in neonates require large clinical researches and long-term follow-up observations for further reliable evaluation.