中国实用儿科杂志2024,Vol.39Issue(1):36-42,7.DOI:10.19538/j.ek2024010607
益生菌在儿童抗生素相关性腹泻应用进展
Application progress of probiotics in the antibiotic-associated diarrhea in children
邹标 1舒赛男1
作者信息
- 1. 华中科技大学同济医学院附属同济医院儿科,湖北武汉 430030
- 折叠
摘要
Abstract
Antibiotic-associated diarrhea(AAD)is a common complication of antibiotic treatment.It is characterized by the disruption of the gut microbiota,causing the decrease of intestinal short chain fatty acid(SCFA)concentrations,accumulation of luminal carbohydrates and colonic bile acids,changes in water and electrolyte absorption,and ultimately diarrhea.Many randomized controlled trials have shown the benefits of probiotics in preventing AAD.Although adverse events have been reported for probiotics,they still are broadly considered to be a safe and inexpensive preventative treatment option for AAD and other gastrointestinal disorders.This review summarized the effects of probiotics on children's AAD,in order to guide its rational application.关键词
益生菌/抗生素相关性腹泻/预防/治疗/儿童Key words
probiotics/antibiotic-associated diarrhea/prev-ention/treatment/child分类
医药卫生引用本文复制引用
邹标,舒赛男..益生菌在儿童抗生素相关性腹泻应用进展[J].中国实用儿科杂志,2024,39(1):36-42,7.