中国听力语言康复科学杂志2024，Vol.22Issue(1)：42-45,78,5.DOI:10.3969/j.issn.1672-4933.2024.01.012
小脑性缄默综合征言语语言障碍研究进展
Advances in Research on Speech and Language Disturbances in Cerebellar Mutism Syndrome
摘要
Abstract
Cerebellar mutism syndrome(CMS)is the most common complication following surgical resection of pediatric posterior fossa tumors,with an incidence ranging approximately from 8%to 40%.CMS is characterized by transient speech and language disturbances,motor dysfunction,emotional issues,and cognitive impairments.Speech disturbances typically manifest on the day of surgery or within a few days,with most recovering gradually within three months postoperatively.However,some patients may experience prolonged speech issues.Clinical manifestations of speech and language disturbances in CMS are diverse and include complete mutism,speech regression,reduced vocal intensity,and articulation disorders,among others.The course of CMS is complex,and different patients may exhibit different types of language disorders.Hypotheses regarding the pathogenesis of CMS include the cerebellar-cerebral circuit damage hypothesis,particularly the cerebellar-thalamo-cortical circuit(DTC),the Guillain-Mollaret triangle circuit,damage to the vermis of the cerebellum,and the postoperative edema hypothesis,among others.The research regarding the different types of language impairment among CMS is lack and need more attention.Future research directions include the development of specialized speech and language assessment tools,the establishment of prognostic models for CMS,aiming to better understand CMS and its speech and language disturbances,and enhancing the precision of diagnosis and treatment.关键词
小脑性缄默综合征/言语语言障碍/发病机制/研究进展Key words
Cerebellar mutism syndrome/Speech and language disturbances/Pathogenesis/Research progress分类
医药卫生引用本文复制引用
杨伟,刘恒鑫,陈邦绮,尹光恒,巴甫仁,葛明..小脑性缄默综合征言语语言障碍研究进展[J].中国听力语言康复科学杂志,2024,22(1):42-45,78,5.基金项目
北京市医院管理中心临床医学发展专项(XMLX202144) （XMLX202144）
