中国心理卫生杂志2024，Vol.38Issue(1)：33-41,9.DOI:10.3969/j.issn.1000-6729.2024.01.005
双相Ⅰ型障碍和双相Ⅱ型患者人口学和临床特征的比较
Comparison of demographic and clinical characteristics of bipolar Ⅰ disorder and bipolar Ⅱ disorder
摘要
Abstract
Objective:To compare demographic characteristics,clinical characteristics,therapeutic characteris-tics and physiological indicators of patients with bipolar Ⅰ disorder and bipolar Ⅱ disorder.Methods:A total of 381 patients with bipolar disorder(BD)diagnosed by the Diagnostic and Statistical Manual of Mental Disorders 5 th Edi-tion(DSM-5)were selected,including 302 patients with BD-Ⅰ(79.27％),74 patients with BD-Ⅱ(19.42％)and 5 patients with other specific and related disorders(1.31％).Demographic and clinical characteristics were collected with self-designed clinical information questionnaire.Multivariate logistic regression and multivariate linear regres-sion analysis were used for analysis.Results:Compared with patients with BD-Ⅱ,patients with BD-Ⅰ had more risk to have psychotic features(OR=5.75,95％CI:2.82-11.76),longer disease duration,and more repeated transcra-nial magnetic therapy(OR=3.09,95％CI:1.02-9.35),higher uric acid,total cholesterol and high-density lipo-protein.BD-Ⅰ in Han nationality was more common(OR=11.50,95％CI:1.76-75.30),and had lower education level(OR=10.22,95％CI:1.16-89.77),and less family history of psychosis(OR=2.34,95％CI:1.01-5.42).Conclusion:There are significant differences between BD-Ⅰ and BD-Ⅱ in demographic and clinical charac-teristics,treatment status,and physiological indicators,which could provide clues for exploring the pathogenesis of bipolar disorder.关键词
双相Ⅰ型障碍/双相Ⅱ型障碍/临床特征/生理指标/治疗Key words
bipolar Ⅰ disorder/bipolar Ⅱ disorder/clinical characteristics/physiological indicators/treat-ment patterns分类
医药卫生引用本文复制引用
周莉,李中才,李弼,李志鹏,曾庆园,沈宗霖,陈文明,刘肇瑞,卢瑾,谢依玲,张婷婷,黄悦勤,周亮,刘燕,刘波,章杰,龚元东..双相Ⅰ型障碍和双相Ⅱ型患者人口学和临床特征的比较[J].中国心理卫生杂志,2024,38(1):33-41,9.基金项目
国家重点研发计划(2017YFC0907800). （2017YFC0907800）
