中国医科大学学报2024，Vol.53Issue(1)：8-14,7.DOI:10.12007/j.issn.0258-4646.2024.01.002
平肝祛湿同治法对中青年高血压患者中医证候、不良事件及预后相关指标的影响
Effects of Pingan qushi prescription on traditional Chinese medicine syndrome,adverse events,and compliance in young and middle-aged patients with hypertension
摘要
Abstract
Objective To investigate the effects of the Pingan qushi prescription on traditional Chinese medicine syndrome,adverse events,and compliance in young and middle-aged hypertensive patients.Methods One hundred thirty-two young and middle-aged patients with hypertension were selected and randomly divided into two groups.After elimination,64 cases were included in each group.For 2 months,the control group was treated with irbesartan tablets,and the observation group underwent the Pingan qushi prescription based on the control group.The blood pressure,curative effect,traditional Chinese medicine syndrome score,safety,adverse events,and prognosis-related indicators were compared between the two groups.Results The total effective rate of the observation group(96.88%,92.19%)was higher than that of the control group(82.52%,78.13%),and the difference was statistically significant(P = 0.005,P = 0.025).After 1 and 2 months of treatment,the blood pressure,syndrome scores,ALD,PRA,AngⅡ,and ET-1 in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).There was no sig-nificant difference in the incidence of adverse reactions between the two groups(P>0.05).There was no statistically significant difference(P>0.05)in the incidence of adverse events during treatment between the observation group(1.56%)and control group(10.94%).Conclusion The treatment of young and middle-aged community patients with hypertension undergoing the Pingan qushi pre-scription can further improve patients'symptoms,increase blood pressure control,promote prognosis improvement.关键词
平肝祛湿同治法/中青年/高血压Key words
Pingan qushi prescription/young and middle-aged/hypertension分类
医药卫生引用本文复制引用
柴松波,杜亚康,张淑娟,兀江波,王晓飞..平肝祛湿同治法对中青年高血压患者中医证候、不良事件及预后相关指标的影响[J].中国医科大学学报,2024,53(1):8-14,7.基金项目
国家自然科学基金(82204981) （82204981）
河南省中医药拔尖人才培养项目专项课题(2022ZYBJ29) （2022ZYBJ29）
