中国医科大学学报2024，Vol.53Issue(1)：86-90,93,6.DOI:10.12007/j.issn.0258-4646.2024.01.014
运动相关的irisin在糖尿病及其并发症中的作用
Role of exercise-related irisin in diabetes mellitus and its complications
摘要
Abstract
Diabetes mellitus is a complex metabolic disease involving multiple organ systems in the body.In recent years,its global incidence rate has increased year by year.In China,the blood glucose control of patients with diabetes mellitus who receive oral hypogly-cemic agents or insulin treatment remains poor.In the early disease stages,exercise is important to control blood glucose levels.Recently,many studies have found that the occurrence of type 2 diabetes mellitus was related to declining levels of irisin,an exercise-related muscle factor.Furthermore,studies have found that irisin improved insulin resistance,promoted the production of pancreatic isletβcells,and affected the body's glucose and lipid metabolism.In addition,its levels were also implicated in the occurrence of various complications,such as diabetic nephropathy and diabetes-related cardiovascular diseases.This article summarizes and analyzes the role of irisin in the occurrence and development of diabetes mellitus and further describes its impact and mechanism on various diabetic complications.关键词
鸢尾素/糖尿病/2型糖尿病/妊娠糖尿病/运动Key words
irisin/diabetes mellitus/type 2 diabetes mellitus/gestational diabetes mellitus/exercise分类
医药卫生引用本文复制引用
姜禹彤,丁璟,张祎,张艺萍,邱吉巍,魏迎亮..运动相关的irisin在糖尿病及其并发症中的作用[J].中国医科大学学报,2024,53(1):86-90,93,6.基金项目
国家自然科学基金(31900847) （31900847）
