中国药物评价2023，Vol.40Issue(6)：512-516,5.
环硅酸锆钠治疗血液透析伴高钾血症的临床研究进展
Clinical Research Progress of Sodium Zirconium Cyclosilicate in the Treatment of Hemodialysis with Hyperkalemia
摘要
Abstract
Sodium zirconium cyclosilicate is an inorganic crystalline compound that can not be absorbed by the human body and is bound with K+for cation exchange.Its main action site is in the gastrointestinal tract.Hypokalemia activity was observed within 1 h after oral administration in patients with hyperkalemia.Studies have shown that sodium zirconium cyclosilicate can safely and effectively reduce serum potassium in hemodialysis patients with hyperkalemia.However,SZC,as a new ion exchange resin for the treatment of hyperkale-mia,has a short marketing time,and the extent to which it has been proven effective and safe has yet to be widely confirmed.This article aims to summarize the research on the application of sodium zirconium cyclosilicate in hemodialysis patients with hyperkalemia,in order to provide reference for follow-up research.关键词
环硅酸锆钠/高钾血症/血液透析/有效性/不良反应Key words
Sodium zirconium cyclosilicate/Hyperkalemia/Hemodialysis/Effectiveness/Adverse reactions分类
医药卫生引用本文复制引用
安兴宇,李兴德,宋沧桑,毛盼盼,张函舒,王国徽..环硅酸锆钠治疗血液透析伴高钾血症的临床研究进展[J].中国药物评价,2023,40(6):512-516,5.基金项目
云南省临床药学中心建设项目 （）
云南省卫生健康委员会医学领军人才培养项目(编号:L-2018012) （编号:L-2018012）
云南省科技厅科技计划项目(202301AY070001-112) （202301AY070001-112）
昆明市卫生科技人才培养项目(2022-SW(带头)-32) （2022-SW(带头）
