摘要
Abstract
Objective:To compare the effects of Tomoxetine and Aripiprazole on impulsive behavior and cognitive function in children with attention deficit hyperactivity disorder.Method:A total of 102 children with attention deficit hyperactivity disorder admitted to the Third People's Hospital of Yichun from July 2020 to December 2022 were selected,and divided into study group(treated with Tomoxetine)and control group(treated with Aripiprazole)by random number table method,with 51 cases in each group.The effect of treatment was evaluated after 1 month of continuous treatment.The combined Raven's test(CRT)score,the Montreal cognitive function assessment scale(MoCA)score,the clinical efficacy,and the adverse reactions were compared between the two groups.Result:After treatment,comparative reasoning ability,similar comparison ability,perceptual discrimination ability,series relationship ability,abstract reasoning ability,and IQ number scores of both groups were increased compared to those before treatment,the differences were statistically significant(P＜0.05),and those in the study group were higher than those in the control group(P＜0.05).Before treatment,there was no statistical difference in MoCA score between the two groups(P＞0.05);after treatment,MoCA scores of both groups were increased compared to those before treatment,the differences were statistically significant(P＜0.05),and that in the study group was higher than that in the control group,the difference was statistically significant(P＜0.05).The clinical efficacy of the study group was better than that of the control group(P＜0.05).The incidence of adverse reactions in the study group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion:Compared with Aripiprazole,Tomoxetine can effectively improve comprehensive ability,reduce impulsive behavior,improve cognitive function and clinical efficacy,and reduce the incidence of adverse reactions in children with attention deficit hyperactivity disorder.关键词
托莫西汀/阿立哌唑/注意缺陷多动障碍/不良反应/冲动行为Key words
Tomoxetine/Aripiprazole/Attention deficit hyperactivity disorder/Adverse reactions/Impulsive behavior
