中国医学前沿杂志（电子版）2023，Vol.15Issue(12)：1-7,7.DOI:10.12037/YXQY.2023.12-01
新型信使核糖核酸疫苗研究:开启革命性疫苗科学——解读2023年诺贝尔生理学或医学奖
New mRNA vaccine research:Pioneering revolutionary vaccine science——Interpretation of the 2023 Nobel Prize in Physiology or Medicine
王琪 1张杰 1赵学森 1王玺 1金荣华1
作者信息
- 1. 首都医科大学附属北京地坛医院传染病研究所 新发突发传染病研究北京市重点实验室,北京 100015||北京市感染性疾病研究中心,北京 100015||国家传染病医学中心 首都医科大学附属北京地坛医院,北京 100015
- 折叠
摘要
Abstract
During the coronavirus pneumonia pandemic,the rapid introduction of mRNA vaccines has saved countless lives.This success can be attributed to advances in mRNA technology and chemical design,including the development of mRNA base modifications and delivery platforms.This article aims to summarize and discuss the differences between traditional vaccines and emerging mRNA vaccine technology,as well as the key chemical design and principles of mRNA vaccines.Additionally,potential biomedical applications of mRNA vaccines will be explored,including expected breakthroughs in cancer treatment and infectious disease prevention and control.These developments are of significant importance for improving human health and driving medical progress.关键词
mRNA疫苗/碱基修饰/mRNA递送系统Key words
mRNA vaccine/Base modifications/mRNA delivery systems引用本文复制引用
王琪,张杰,赵学森,王玺,金荣华..新型信使核糖核酸疫苗研究:开启革命性疫苗科学——解读2023年诺贝尔生理学或医学奖[J].中国医学前沿杂志（电子版）,2023,15(12):1-7,7.
