中国医学装备2024，Vol.21Issue(1)：15-20,6.DOI:10.3969/j.issn.1672-8270.2024.01.003
闪光放射治疗对比常规放射治疗在放射性肺损伤中的机制探索
Study on the mechanism of lung injury induced by ultra-high dose rate Flash radiation therapy versus traditional radiotherapy
王瑶 1俞伟 2张沛 2戴相昆 2刘畅 3曲宝林2
作者信息
- 1. 解放军总医院第一医学中心放射治疗科 北京 100853||解放军总医院京东医疗区综合内科 北京 101100
- 2. 解放军总医院第一医学中心放射治疗科 北京 100853
- 3. 解放军总医院京东医疗区综合内科 北京 101100
- 折叠
摘要
Abstract
Radiotherapy is an important means to treat lung cancer,but it is easy to cause lung injury and reduce the quality of life of patients.Flash radiotherapy(FLASH-RT)has attracted attention due to its extremely short radiation duration and high dose rate,which can reduce toxicity of normal tissue while ensures treatment intensity of tumor.Whether Flash-RT can reduce radiation-induced lung injury has become an important research topic in recent years.Based on the literature analysis method,this review systematically assessed the effects and mechanisms of Flash-RT and radiotherapy with conventional dose rate on lung injury through searching relevant literatures at home and abroad,so as to provide scientific basis for the treatment of patients with lung cancer by reviewing the comparisons about the effects and mechanisms between Flash-RT and radiotherapy with conventional dose rate on lung injury.Compared with radiotherapy with conventional radiation rate,Flash-RT can significantly reduce lung injury and improve quality of life of patients.It is still demanded to explore the Flash-RT mechanism in future,so as to develop the Flash-RT instrument that is suitable for different tumors and to conduct larger-scale clinical researches.关键词
超高剂量率/闪光放射治疗(Flash-RT)/常规剂量率放疗/肺损伤/放射治疗技术Key words
Super-high dose rate/Flash radiotherapy(Flash-RT)/Radiotherapy with conventional dose rate/Lung injury/Radiotherapy technique分类
医药卫生引用本文复制引用
王瑶,俞伟,张沛,戴相昆,刘畅,曲宝林..闪光放射治疗对比常规放射治疗在放射性肺损伤中的机制探索[J].中国医学装备,2024,21(1):15-20,6.
