药师干预对外科手术人血白蛋白使用的影响OACSTPCD

Objective To investigate the effect of pharmacists'intervention on the use of human serum albumin(HSA)in surgery.Methods According to the domestic,foreign guidelines and the actual status of the hospital,the comment standards of HSA were formulated,on the basis,the use of HSA was intervened by clinical pharmacists.A total of 1 632 cases underwent surgery(from January to July 2021,before the intervention)and 3 205 cases underwent surgery(from August 2021 to August 2022,after the intervention)in the Beijing Chest Hospital Affiliated to Capital Medical University were selected.The patients'gender,age,hospital stay,surgical category,proportion of wound healing≥grade two and use of HSA before and after the intervention were compared,the rationality of HSA use and comment effect was evaluated.Results There was no significant difference in patients'gender,age,surgical category of thoracic surgery and orthopedics and proportion of wound healing≥grade two before and after the intervention(P>0.05).Compared with that before intervention,the hospital stay of patients after intervention significantly decreased(P<0.01).The HSA dosage per capita significantly decreased from(64.5±43.8)g before intervention to(54.1±50.7)g after intervention,its use rate significantly decreased from 70.77%to 26.83%,and its irrational use rate significantly decreased from 95.67%to 42.09%(P<0.01).The HSA costs significantly decreased from CNY(2 709±1 841)before intervention to CNY(2 272±2 132)after intervention(P<0.01),with the ranking decreasing from the fifth before intervention to the eighteenth after intervention,the total costs,drug costs and drug proportion also decreased accordingly.Conclusion When the hospital stay decreases,the pharmacists'intervention on the use of HSA in surgery can decrease the average dosage,use rate and irrational use rate of HSA,as well as the patients'total cost,drug costs and drug proportion.