中国药业2024，Vol.33Issue(2)：121-124,4.DOI:10.3969/j.issn.1006-4931.2024.02.030
1例脑心通胶囊致迟发性腹型过敏性紫癜用药分析
Medication Analysis for Delayed Henoch-Schonlein Purpura Induced by Naoxintong Capsules:A Case Report
何芳 1牟燕 2韩毅2
作者信息
- 1. 山东省滨州市人民医院,山东 滨州 256600
- 2. 山东第一医科大学第一附属医院·山东省千佛山医院,山东 济南 250014
- 折叠
摘要
Abstract
Objective To promote the rational application of Naoxintong Capsules in clinical practice.Methods The treatment process of a patient with delayed Henoch-Schonlein purpura induced by Naoxintong Capsules in the Shandong Provincial Qianfoshan Hospital was retrospectively analyzed.Based on the VigiAccess and literature,the correlation of Naoxintong Capsules with adverse drug reactions(ADRs)was evaluated by the Naranjo's ADR evaluation scale,and the clinical characteristics of this ADR were explored.Results After use of Naoxintong Capsules,the patient experienced paroxysmal abdominal pain complicated with gastrointestinal bleeding.After symptomatic treatment with Methylprednisolone Tablets,Bacillus Licheniformis Capsule,Live and Compound Glutamine Entersoluble Capsules,the patient's rash significantly improved,and she did not experienced any abdominal pain or diarrhea.The patient's severe Henoch-Schonlein purpura was likely related to Naoxintong Capsules(the score of Naranjo's ADR evaluation scale was six points).Conclusion Naoxintong Capsules can induce Henoch-Schonlein purpura,but this ADR is not recorded or warned in the drug instructions.Clinical pharmacists and physicians should strengthen pharmaceutical care,pharmaceutical manufacturers and medical staff should strengthen pharmacovigilance,and relevant departments should revise drug instructions if necessary.关键词
脑心通胶囊/腹型过敏性紫癜/迟发性/药品不良反应/药学监护Key words
Naoxintong Capsules/Henoch-Schonlein purpura/delayed/adverse drug reaction/pharmaceutical care分类
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何芳,牟燕,韩毅..1例脑心通胶囊致迟发性腹型过敏性紫癜用药分析[J].中国药业,2024,33(2):121-124,4.
