中国中医药信息杂志2024，Vol.31Issue(2)：11-15,5.DOI:10.19879/j.cnki.1005-5304.202212238
基于"虚气留滞"理论探讨慢性心力衰竭微炎症状态病机及中药防治
Exploration on the Pathogenesis of Micro-inflammatory State in Chronic Heart Failure Based on the Theory of"Deficiency Qi Retention"and Its TCM Prevention and Treatment
摘要
Abstract
Chronic heart failure(CHF)is a common and frequent clinical condition with complex pathogenesis.The micro-inflammatory state exists in the development of CHF and is manifested by a continuous increase in inflammatory proteins and inflammatory cytokines in the circulation,affecting the body's metabolism and immune function.Micro-inflammatory state of CHF belongs to the syndrome of deficiency in nature and excess in superficiality in the TCM field.The basic pathogenesis of CHF is"deficiency qi retention";the nature is the deficiency of heart energy and the superficiality is retention of qi,blood stagnation,phlegm,water and dampness,with"deficiency,stagnation and water"running throughout the disease.Therefore,based on the theory of"deficiency qi retention",this article took"reinforcing deficiency and removing stagnation"as its basic treatment method,regulated the body's immunity and inflammatory indicators such as serum high-sensitivity C-reactive protein,tumor necrosis factor-α,in order to alleviate the micro-inflammatory state,which is of great significance for the prevention and treatment of CHF.关键词
慢性心力衰竭/微炎症状态/虚气留滞/中医药Key words
chronic heart failure/micro-inflammatory state/deficiency qi retention/TCM分类
医药卫生引用本文复制引用
曾清华,魏佳明,王子焱,黄爱思,郭志华..基于"虚气留滞"理论探讨慢性心力衰竭微炎症状态病机及中药防治[J].中国中医药信息杂志,2024,31(2):11-15,5.基金项目
国家自然科学基金(82174343) （82174343）
湖南省重点研发计划(2022SK2012) （2022SK2012）
湖南省自然科学基金(2021JJ30492、2021JJ30495) （2021JJ30492、2021JJ30495）
