基于"毒伏焦膜"理论探讨免疫性复发性流产病因病机OACSTPCD
Discussion on Etiology and Pathogenesis of Recurrent Spontaneous Abortion Caused by Immune Factors Based on"Latent Toxic Hiding in Membrane"
免疫因素为复发性流产的重要病因,免疫失衡影响胚胎种植和生长发育.免疫性复发性流产的病因病机目前尚未形成一致观点.本文以中医伏毒理论为基础,结合免疫异常物质在体内动态变化的病理机制,提出伏毒为免疫性复发性流产的关键病因,进而阐述伏毒具有热瘀互结、蛰伏胞宫,正虚毒伏、胎成诱发的致病特点.认为伏毒滞于焦膜为发病机制,存在伏毒阻滞内通性膜系、外通性膜系等多种病理变化,应以益气养血、补肾固冲、清热凉血、活血化瘀为基本治法,为中医辨治免疫性复发性流产提供理论参考.
Immune factors play an important role in recurrent spontaneous abortion(RSA),and immune imbalance affects embryo implantation,growth,and development.There is currently no consensus on the etiology and pathogenesis of RSA caused by immune factors.Based on the theory of latent toxic in TCM and combined with the pathological mechanism of the dynamic changes of immune abnormal substances in the body,this article proposed that latent toxic is the key cause of RSA caused by immune factors.Furthermore,it expounded the pathogenic characteristics of latent toxic:combination of heat and blood stasis hidden in the womb,and latent toxic plays a role in embryo formation under qi deficiency conditions.It is established that latent toxin stagnation in the membrane is the pathogenic mechanism.Moreover,this article revealed the variable pathological changes such as the blockage of the inner membrane system and the outer membrane system.Treatment should be based on the basic methods of tonifying qi and nourishing blood,tonifying kidney to secure the Thoroughfare Vessel,clearing heat and cooling blood,promoting blood circulation and removing blood stasis.This article could provide a theoretical basis for TCM syndrome differentiation and treatment of RSA caused by immune factors.
袁明慧;张建伟;张良;荣远航
山东中医药大学,山东 济南 250000山东中医药大学附属医院,山东 济南 250000
中医学
免疫性复发性流产伏毒焦膜病因病机
recurrent spontaneous abortion caused by immune factorslatent toxicmembraneetiologypathogenesis
《中国中医药信息杂志》 2024 (002)
16-20 / 5
国家自然科学基金青年基金(N82205174);山东省自然科学基金面上项目(ZR2020MH363);山东省研究生教育教学改革研究项目(SDYJG19147);山东省中医药科技面上项目(2021M176)
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