中医药信息2024，Vol.41Issue(1)：65-78,14.DOI:10.19656/j.cnki.1002-2406.20240113
白术化学成分、药理作用研究进展及质量标志物预测
Research Progress of Chemical Constituents,Pharmacological Action and Quality Marker Prediction of Largehead Atractylodes Rhizome
摘要
Abstract
Largehead atractylodes rhizome is a commonly used as a major medicinal material,which can fortify the spleen,replenish qi,dry dampness and induce diuresis,be antagonistic to perspiration and prevent abortion.In this paper,we review the chemical constituents and pharmacological effects of the medicinal.On this basis,quality marker was predicted from the perspectives of plant affinity,component specificity,effectiveness,measurability and medicinal properties.We found that the chemical components of largehead atractylodes rhizome are diverse,including sesquiterpenoids,flavonoids,polysaccharides,polyacetylides,phenolic acids,glycosides and so on.These chemical components have anti-inflammatory,anti-tumor,gastrointestinal regulation,antibacterial,antioxidant,liver protection,cardiovascular and nervous system protection,immune regulation and other effects,and can be used for the treatment and prevention of gastrointestinal,nervous system and liver diseases.Lactone Ⅰ,Ⅱ,Ⅲ and other lactones and polysaccharide components can be used as alternative components of quality marker.关键词
白术/化学成分/药理作用/质量标志物/白术内酯Key words
Largehead atractylodes rhizome/Chemical constituents/Pharmacological action/Quality marker/Atractylenolide引用本文复制引用
刘棣文,何莉莉,崔娜,王秋红..白术化学成分、药理作用研究进展及质量标志物预测[J].中医药信息,2024,41(1):65-78,14.基金项目
国家重点研发计划项目(2018YFC1707100) （2018YFC1707100）
广东省重点领域研发计划(2020B111112002) （2020B111112002）
黑龙江省"头雁"团队支持项目(黑龙江省头雁行动领导小组文件[2019]5号) （黑龙江省头雁行动领导小组文件[2019]5号）
