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Environmental enrichment in combination with Bifidobacterium breve HNXY26M4 intervention amplifies neuroprotective benefits in a mouse model of Alzheimer''''s disease by modulating glutamine metabolism of the gut microbiome

Guangsu Zhu Min Guo Jianxin Zhao Hao Zhang Gang Wang Wei Chen

Food Science and Human Wellness2024，Vol.13Issue(2)：P.982-992,11.

Food Science and Human Wellness2024，Vol.13Issue(2)：P.982-992,11.DOI:10.26599/FSHW.2022.9250084

Environmental enrichment in combination with Bifidobacterium breve HNXY26M4 intervention amplifies neuroprotective benefits in a mouse model of Alzheimer''''s disease by modulating glutamine metabolism of the gut microbiome

Guangsu Zhu ¹Min Guo ¹Jianxin Zhao ²Hao Zhang ²Gang Wang ²Wei Chen³

作者信息

1. State Key Laboratory of Food Science and Resources,Jiangnan University,Wuxi 214122,China School of Food Science and Technology,Jiangnan University,Wuxi 214122,China
2. State Key Laboratory of Food Science and Resources,Jiangnan University,Wuxi 214122,China School of Food Science and Technology,Jiangnan University,Wuxi 214122,China (Yangzhou)Institute of Food Biotechnology,Jiangnan University,Yangzhou 225004,China National Engineering Center of Functional Food,Jiangnan University,Wuxi 214122,China
3. State Key Laboratory of Food Science and Resources,Jiangnan University,Wuxi 214122,China School of Food Science and Technology,Jiangnan University,Wuxi 214122,China National Engineering Center of Functional Food,Jiangnan University,Wuxi 214122,China
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摘要

关键词

Alzheimer’s disease/Bifidobacterium breve/Environmental enrichment/Glutamine metabolism/Microbiota-gut-brain axis

分类

轻工纺织

引用本文复制引用

Guangsu Zhu,Min Guo,Jianxin Zhao,Hao Zhang,Gang Wang,Wei Chen..Environmental enrichment in combination with Bifidobacterium breve HNXY26M4 intervention amplifies neuroprotective benefits in a mouse model of Alzheimer''''s disease by modulating glutamine metabolism of the gut microbiome[J].Food Science and Human Wellness,2024,13(2):P.982-992,11.

基金项目

supported by the National Natural Science Foundation of China(31972052,32021005,31820103010) （31972052,32021005,31820103010）

the Fundamental Research Funds for the Central Universities(JUSRP22006,JUSRP51501) （JUSRP22006,JUSRP51501）

the Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province。（）

Food Science and Human Wellness

ISSN：2097-0765

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