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Multiplex gene editing reduces oxalate production in primary hyperoxaluria type 1

Rui Zheng De-Xin Zhang Yan-Jiao Shao Xiao-Liang Fang Lei Yang Ya-Nan Huo Da-Li Li Hong-Quan Geng

动物学研究2023，Vol.44Issue(6)：993-1002,10.

动物学研究2023，Vol.44Issue(6)：993-1002,10.DOI:10.24272/j.issn.2095-8137.2022.495

Multiplex gene editing reduces oxalate production in primary hyperoxaluria type 1

Rui Zheng ¹De-Xin Zhang ¹Yan-Jiao Shao ¹Xiao-Liang Fang ¹Lei Yang ²Ya-Nan Huo ²Da-Li Li ²Hong-Quan Geng³

作者信息

1. Department of Pediatric Urology,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China
2. Shanghai Key Laboratory of Regulatory Biology,Institute of Biomedical Sciences and School of Life Sciences,East China Normal University,Shanghai 200241,China
3. Division of Pediatric Urology,Children's Hospital of Fudan University,Shanghai 201102,China
折叠

摘要

关键词

Hyperoxaluria/Genome editing/Lactate dehydrogenase/Hydroxyacid oxidase 1

Key words

Hyperoxaluria/Genome editing/Lactate dehydrogenase/Hydroxyacid oxidase 1

引用本文复制引用

Rui Zheng,De-Xin Zhang,Yan-Jiao Shao,Xiao-Liang Fang,Lei Yang,Ya-Nan Huo,Da-Li Li,Hong-Quan Geng..Multiplex gene editing reduces oxalate production in primary hyperoxaluria type 1[J].动物学研究,2023,44(6):993-1002,10.

基金项目

This work was partially supported by the Science and Technology Commission of Shanghai Municipality(22YF1426900,20140900200)and National Natural Science Foundation of China(32001057) （22YF1426900,20140900200）

动物学研究

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ISSN：0254-5853

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