动物学研究2023，Vol.44Issue(6)：1003-1014,12.DOI:10.24272/j.issn.2095-8137.2023.108
Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model
Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model
Zhongyun Zhang 1Yuhuan Gong 2Mingjun Jia 2Xiaoyu Zhang 2Peng Ning 2Mei Liu 3Xiaoyan Li 3Xiaomeng Shi 3Wenjun Liu 4George F.Gao 5Guang Ning 1Ning Zhang 2Jiqiu Wang 1Yuhai Bi 6Xuancheng Lu 3Min Zhou 7Xiaoxiang Yan 8Weiqiong Gu 1Jingru Yang 9Qin Zhang 3Cheng Zhang2
作者信息
- 1. Department of Endocrinology and Metabolism,Shanghai Institute of Endocrine and Metabolic Diseases,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China||Shanghai National Clinical Research Center for Metabolic Diseases,Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China,Shanghai National Center for Translational Medicine,Shanghai 200025,China
- 2. CAS Key Laboratory of Pathogen Microbiology and Immunology,Institute of Microbiology,Center for Influenza Research and Early-warning(CASCIRE),CAS-TWAS Center of Excellence for Emerging Infectious Diseases(CEEID),Chinese Academy of Sciences,Beijing 100101,China
- 3. Laboratory Animal Center,Chinese Center for Disease Control and Prevention(China CDC),Beijing 102206,China
- 4. CAS Key Laboratory of Pathogen Microbiology and Immunology,Institute of Microbiology,Center for Influenza Research and Early-warning(CASCIRE),CAS-TWAS Center of Excellence for Emerging Infectious Diseases(CEEID),Chinese Academy of Sciences,Beijing 100101,China||University of Chinese Academy of Sciences,Beijing 100049,China
- 5. CAS Key Laboratory of Pathogen Microbiology and Immunology,Institute of Microbiology,Center for Influenza Research and Early-warning(CASCIRE),CAS-TWAS Center of Excellence for Emerging Infectious Diseases(CEEID),Chinese Academy of Sciences,Beijing 100101,China||Laboratory Animal Center,Chinese Center for Disease Control and Prevention(China CDC),Beijing 102206,China||University of Chinese Academy of Sciences,Beijing 100049,China
- 6. CAS Key Laboratory of Pathogen Microbiology and Immunology,Institute of Microbiology,Center for Influenza Research and Early-warning(CASCIRE),CAS-TWAS Center of Excellence for Emerging Infectious Diseases(CEEID),Chinese Academy of Sciences,Beijing 100101,China||School of Laboratory Medicine and Life Sciences,Wenzhou Medical University,Wenzhou,Zhejiang 325000,China||University of Chinese Academy of Sciences,Beijing 100049,China
- 7. Department of Respiratory and Critical Care Medicine,Institute of Respiratory Diseases,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China
- 8. Department of Cardiology,Institute of Cardiovascular Diseases,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China
- 9. School of Laboratory Medicine and Life Sciences,Wenzhou Medical University,Wenzhou,Zhejiang 325000,China
- 折叠
摘要
关键词
SARS-CoV-2/Diabetes/Mouse model/Heparin/Antiviral therapyKey words
SARS-CoV-2/Diabetes/Mouse model/Heparin/Antiviral therapy引用本文复制引用
Zhongyun Zhang,Yuhuan Gong,Mingjun Jia,Xiaoyu Zhang,Peng Ning,Mei Liu,Xiaoyan Li,Xiaomeng Shi,Wenjun Liu,George F.Gao,Guang Ning,Ning Zhang,Jiqiu Wang,Yuhai Bi,Xuancheng Lu,Min Zhou,Xiaoxiang Yan,Weiqiong Gu,Jingru Yang,Qin Zhang,Cheng Zhang..Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model[J].动物学研究,2023,44(6):1003-1014,12.基金项目
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(CAS)(XDB29010102) （CAS）
National Natural Science Foundation of China(NSFC)(91957124,82161148010,32041010) （NSFC）
Self-supporting Program of Guangzhou Laboratory(SRPG22-001) （SRPG22-001）
National Science and Technology Infrastructure of China(National Pathogen Resource Center-NPRC-32) （National Pathogen Resource Center-NPRC-32）
and Management Strategy of the Tertiary Prevention and Treatment of Diabetes Based on DIP system(supported by China Health Promotion Foundation).Y.B.was supported by the Youth Innovation Promotion Association of CAS(Y2021034)and Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202208) （supported by China Health Promotion Foundation）
