动物营养学报2023，Vol.35Issue(12)：7641-7647,7.DOI:10.12418/CJAN2023.694
植物多糖对内质网应激介导的动物细胞凋亡、炎症和氧化损伤的影响及其作用机制
Effects of Plant Polysaccharides on Endoplasmic Reticulum Stress-Mediated Apoptosis,Inflammation and Oxidative Damage of Animal Cells and Their Mechanisms
摘要
Abstract
The endoplasmic reticulum(ER)is an important organelle responsible for protein folding and modi-fication within cells.Endoplasmic reticulum stress is cellular stress response caused by abnormal accumulation of proteins,which can lead to inflammation,oxidative damage and cell apoptosis and other adverse reactions in animal.Recent studies have shown that plant polysaccharides can relieve ER stress through the pathways related to ER overload response and unfolded protein response mediated by ER,thus protecting animal body from inju-ry.This review reviews the mechanism and research progress of plant polysaccharides in alleviating inflamma-tion,oxidative damage and apoptosis induced by ERS in animals.[Chinese Journal of Animal Nutrition,2023,35(12):7641-7647]关键词
植物多糖/内质网应激/免疫/抗氧化/细胞凋亡Key words
plant polysaccharides/endoplasmic reticulum stress/immune/antioxidation/cell apoptosis分类
农业科技引用本文复制引用
陈宇,郑彦楷,李大彪,邢媛媛..植物多糖对内质网应激介导的动物细胞凋亡、炎症和氧化损伤的影响及其作用机制[J].动物营养学报,2023,35(12):7641-7647,7.基金项目
内蒙古自然科学基金青年基金项目(2023QN03014) （2023QN03014）
高层次人才引进科研启动项目(NDYB2021-3) （NDYB2021-3）
高水平成果培育专项项目(QF202203) （QF202203）
