动物营养学报2023，Vol.35Issue(12)：7774-7785,12.DOI:10.12418/CJAN2023.706
红曲菌对黄羽肉鸡生长性能、免疫功能、血浆生化指标、抗氧化能力和脂质代谢的影响
Effects of Monascus on Growth Performance,Immune Function,Plasma Biochemical Indexes,Antioxidant Capacity and Lipid Metabolism of Yellow-Feathered Chickens
摘要
Abstract
This experiment was conducted to investigate the effects of Monascus on growth performance,im-mune function,plasma biochemical indexes,antioxidant capacity and lipid metabolism of yellow-feathered chickens,to provide reference for its application in chicken feeding.A total of 288 one-day-old healthy ephedra chickens were randomly divided into 2 groups with 6 replicates in each group and 24 chickens in each replicate(half male and half female).Chickens in the control group were fed a basal diet,and chickens in the Monas-cus group were fed the basal diet supplemented with 500 mg/kg Monascus.The experiment lasted for 51 days.The results showed that compared with the control group:1)The average daily gain of chickens during 22 to 42 days of age and 43 to 51 days of age of Monascus group was significantly increased(P＜0.05),and the ra-tio of feed to gain of chickens during 22 to 42 days of age,43 to 51 days of age and 1 to 51 days of age of Monascus group was significantly decreased(P＜0.05).2)The spleen index of chickens at 21 and 51 days of age of Monascus group was significantly increased(P＜0.05).3)The contents of total protein(TP)and total bilirubin(TBILI)in plasma of chickens at 21 days of age of Monascus group were significantly increased(P＜0.05),and the uric acid(UA)content and aspartate aminotransferase(AST)activity were significantly de-creased(P＜0.05);the TP and TBILI contents and lactate dehydrogenase(LDH)activity in plasma of chick-ens at 51 days of age of Monascus group were significantly increased(P＜0.05),and the UA content and ala-nine aminotransferase(ALT)activity were significantly decreased(P＜0.05).4)The content of interleukin-10(IL-10)in jejunal mucosa of chickens at 21 days of age and content of tumor necrosis factor-α(TNF-α)in jejunal mucosa of chickens at 51 days of age of Monascus group were significantly decreased(P＜0.05),and the content of interleukin-10(IL-10)in jejunal mucosa of chickens at 21 and 51 days of age was signifi-cantly increased(P＜0.05).5)The activities of total superoxide dismutase(T-SOD)and glutathione peroxi-dase(GSH-Px)in liver of chickens of Monascus group were significantly increased(P＜0.05),the kidney malondialdehyde(MDA)content was significantly decreased(P＜0.05),and the kidney GSH-Px activity was significantly increased(P＜0.05).6)The content of high density lipoprotein cholesterol(HDL-C)in plasma of chickens at 21 and 51 days of age and in liver of chickens at 21 days of age of Monascus group was signifi-cantly decreased(P＜0.05),and the content low density lipoprotein cholesterol(LDL-C)content in plasma of chickens at 21 days of age was significantly decreased(P＜0.05).In summary,dietary 500 mg/kg Monascus can improve the growth performance,immune function and antioxidant capacity of yellow-feathered chickens during 1 to 51 days of age,and regulate the lipid metabolism.[Chinese Journal of Animal Nutrition,2023,35(12):7774-7785]关键词
红曲菌/黄羽肉鸡/生长性能/免疫功能/抗氧化能力/脂质代谢Key words
Monascus/yellow-feathered chickens/growth performance/immune function/antioxidant capac-ity/lipid metabolism分类
畜牧业引用本文复制引用
苏青云,熊太第,张盛,叶金玲,罗琦丽,苟钟勇,蒋守群,范秋丽..红曲菌对黄羽肉鸡生长性能、免疫功能、血浆生化指标、抗氧化能力和脂质代谢的影响[J].动物营养学报,2023,35(12):7774-7785,12.基金项目
国家重点研发计划项目(2021YFD1300404) （2021YFD1300404）
广东省重点领域研发计划项目(2020B0202090004) （2020B0202090004）
现代农业产业技术体系国家肉鸡产业技术体系项目(CARS-41) （CARS-41）
广东省自然科学基金项目(2021A1515012412,2021A1515010830,2022A1515012069) （2021A1515012412,2021A1515010830,2022A1515012069）
广州市科技计划项目(202206010168) （202206010168）
广东省农业科学院科技计划项目(202106TD,R2019PY-QF008) （202106TD,R2019PY-QF008）
广东省畜禽育种与营养研究重点实验室开放课题(2021SZ03) （2021SZ03）
