摘要
Abstract
Objective To explore the psychometric characteristics of the Chinese version of the electroconvulsive therapy cognitive assessment(ECCA)in early adult patients with depression.Method The study was conducted at Beijing Anding Hospital,Capital Medical University from January 2021 to December 2022.Finally,a total of 40 early adults with depression and 30 healthy controls were included.ECCA and the Montreal cognitive assessment(MoCA)were performed at three time points in early adults with depression who were treated with electroconvulsive therapy(ECT).That is,before treatment(baseline),after the fifth treatment,and 7-10 days after the end of treatment.Healthy subjects underwent an ECCA assessment.Statistical analysis performed by χ2 test,repeated measurements of ANOVA,t-test,Pearson correlation analysis.Result There were no significant differences in age,gender and years of education between the depression group and the control group(all P>0.05).However,the baseline ECCA score in the early adult depression group was lower than that in the control group[(27.75±1.77)vs(29.10±0.80)points,t=-3.687,P<0.001].The baseline MoCA score was lower than that of the control group[(27.39±0.23)vs(29.60±0.30)points,t=-11.640,P<0.001].Cronbach'α in ECCA internal consistency analysis was 0.811(P<0.001).ECCA scores before ECT[(27.75±1.77)points]>during ECT[(25.17±1.73)points]>after ECT[(21.90±3.67)points](F=13.242,all P<0.001),while MoCA scores at these three time points showed no significant difference(F=1.871,P=0.171).After controlling for gender,age,and education level,the total ECCA score was highly correlated with MoCA(r=0.450,P<0.01)and Hamilton depression scale-17 item(HDRS-17)(r=-0.621,P<0.01)at baseline in early adult patients with depression.Conclusion The Chinese version of ECCA has good psychometric characteristics and can be used as a clinical tool to assess ECT related cognitive impairment in early adult patients with depression.关键词
电休克治疗/成年早期/抑郁症/认知损害Key words
Electroconvulsive therapy/Early adulthood/Depression/Cognitive impairment
