国际生殖健康/计划生育杂志2024，Vol.43Issue(1)：42-47,6.DOI:10.12280/gjszjk.20230383
肠道菌群及肠道代谢物与多囊卵巢综合征的关系
The Relationship between Intestinal Flora,Intestinal Metabolites and Polycystic Ovary Syndrome
摘要
Abstract
Human gut microbiota is rich and diverse,among which gut microbiota can affect host metabolism,immunity and other processes through the brain-gut axis pathway,and then is related to the occurrence and development of a variety of diseases.The changes of intestinal flora in patients with polycystic ovary syndrome(PCOS)are related to clinical features and complications such as insulin resistance,hyperandrogenism,chronic inflammation and metabolic syndrome.Recent studies have shown that intestinal flora may also affect the pathogenesis and pathological process of PCOS through intestinal metabolites such as bile acids,short-chain fatty acids,ceramides and trimethylamine derivatives.In addition,some studies have explored the application of fecal microbiota transplantation,supplementation of probiotics and synbiotics to regulate intestinal flora,in order to provide a theoretical basis for improving the clinical manifestations and related complications of PCOS.关键词
多囊卵巢综合征/胃肠道微生物组/治疗/代谢疾病/肠道代谢物Key words
Polycystic ovary syndrome/Gastrointestinal microbiome/Therapy/Metabolic diseases/Intestinal metabolites引用本文复制引用
周昕玥,李宁,魏林飞,张学红..肠道菌群及肠道代谢物与多囊卵巢综合征的关系[J].国际生殖健康/计划生育杂志,2024,43(1):42-47,6.基金项目
国家自然科学基金(81960273) （81960273）
