华北农学报2023，Vol.38Issue(z1)：393-399,7.DOI:10.7668/hbnxb.20194061
必需氨基酸营养对奶牛乳腺蛋白合成调控的研究进展
Research Progress of Essential Amino Acid Nutrition on the Regulation of Mammary Protein Synthesis in Dairy Cows
摘要
Abstract
With the development of dairy products,milk protein is an important index to evaluate the nutrition-al value of milk.Optimizing feed formulation is one of the key tasks to improve the quality and efficiency of dairy cow production.At present,although feeding rumen-protected amino acids is the most direct and efficient way to im-prove milk protein synthesis of dairy cows,most studies only focus on a single limiting amino acid,ignoring the un-derstanding of amino acid nutritional balance.Amino acid nutrition,as the source and signal substance of milk pro-tein synthesis,affects the absorption and utilization of blood amino acids by cows,but its molecular mechanisms is still unclear.Therefore,this article mainly analyzed the effects and regulation of amino acids on protein synthesis in dairy cows.Firstly,it described the basic pathway of milk protein synthesis and the influence of essential amino acids,non-essential amino acids and combined essential amino acids on milk protein yield and concentration.Sec-ondly,it introduced the impact of the supply of essential amino acids and combined essential amino acids on feed in-take,blood amino acid concentration,blood flow and mammary gland cells of dairy cows,while emphasizing the opti-mal supplemental dose of amino acids required for mammary gland cell culture and the specific regulation of essen-tial amino acids on amino acid transporters and signaling pathways in cellular molecular angle.In summary,through the discussion of the factors and molecular regulation mechanism of mammary gland protein synthesis,it can not only help to optimize the ideal amino acid ratio in feed and scientific production mode,but also provide theoretical refer-ence for improving the synthesis of milk protein by amino acid nutrition in related filed.关键词
奶牛/乳蛋白/氨基酸/乳腺细胞/营养调控Key words
Dairy cow/Milk protein/Amino acids/Mammary gland cells/Nutritional regulation分类
农业科技引用本文复制引用
郭鑫,刘杰,高巧仙,辛国省..必需氨基酸营养对奶牛乳腺蛋白合成调控的研究进展[J].华北农学报,2023,38(z1):393-399,7.基金项目
宁夏回族自治区产业创新重点任务揭榜攻关项目(2021030501) （2021030501）
宁夏重点研发计划项目(2023BCF01037) （2023BCF01037）
