煤炭与化工2023，Vol.46Issue(12)：128-133,150,7.DOI:10.19286/j.cnki.cci.2023.12.031
阿瑞匹坦结构中红外光谱研究
Mid infrared spectral study of arepitan structure
摘要
Abstract
A research method for the structure of aprepitant was established.The aprepitant structure were characterized by the mi-infrared(MIR)spectroscopy.The test found that the infrared absorption mode of aprepitant included C=O structure stretching vibration mode(υ C=O_Arepit(en)),C=C structural stretching vibration mode(υ C=C_Arepiten),CF3 structures asymmetric stretching vibration mode(υ asCF3_Arepiten),C-F structure stretching vibration mode(υC-F-Arepit(en))and C-O structure stretching vibration mode(υ C-O_Arepoten).It has found that the spectral resolution of the deconvolution MIR spectra of the Arepitan structure is superior to the corresponding one-dimensional MIR spectra,second-order derivative MIR spectra,and fourth-order derivative MIR spectra,and can provide richer spectral information.关键词
阿瑞匹坦/结构/一维中红外光谱/二阶导数中红外光谱/四阶导数中红外光谱/去卷积中红外光谱Key words
aprepitant/structure/one-dimensional mid infrared spectroscopy/second-order derivative mid infrared spectroscopy/fourth-order derivative mid infrared spectroscopy/deconvolved mid infrared spectroscopy分类
化学化工引用本文复制引用
王春润,雷晓静,周子轩,常美玲,于宏伟,张勇,常明,王丽欣..阿瑞匹坦结构中红外光谱研究[J].煤炭与化工,2023,46(12):128-133,150,7.基金项目
河北科技大学大学生创新创业孵化项目(2023A015) （2023A015）
石家庄市麻醉药技术创新中心项目(2023) （2023）
河北省生物制药国际联合中心项目(2023) （2023）
