1 701例儿童血清过敏原特异性IgE检测结果分析OACSTPCD

Objective To investigate the status of allergen allergy in children in the southwest area of Shanghai,and to provide reference for the prevention,diagnosis and treatment of allergic diseases in children in this area.Methods A total of 1 701 children aged 0-6 years with suspected allergies who visited the hospital from December 2019 to August 2022 were selected as the research objects.Serum total immunoglobulin E(IgE)and specific IgE(sIgE)antibody levels were detected by fluorescent enzyme immunoassay.The distri-bution of serum allergen sIgE was analyzed,and the correlation of sensitization with different allergens was compared.Results The positive rate of dust mites was the highest[49.2％(414/841)],followed by house-hold dust mites[48.6％(409/841)],milk[43.5％(366/841)],egg white[36.7％(309/841)]and mixed fungi[16.4％(138/841)].The positive rate of above allergens in boys were higher than those in girls.The positive rate of inhaled allergens increased with age,and food allergen sensitization mostly occurred in early in-fancy.The serum sIgE level of inhaled allergens was higher than that of food allergens.Household dust mites was a positive correlation with dust mites,crab and shrimp(P＜0.05).Conclusion Mite,milk and egg white are the main allergens of children in southwest Shanghai.Boys were more susceptible to allergies than girls.The correlation between allergens with similar attributes is stronger,and inhaled allergens are also associated with food allergens.