检验医学与临床2024，Vol.21Issue(2)：170-173,4.DOI:10.3969/j.issn.1672-9455.2024.02.006
苏州某中医院血流感染病原菌分布及耐药性分析
Distribution and drug resistance of pathogens causing bloodstream infection in a traditional Chinese medicine hospital in Suzhou
摘要
Abstract
Objective To analyze the distribution and drug resistance of pathogenic bacteria in blood cul-ture samples,and to provide the basis for clinical infection control.Methods The pathogens isolated from blood culture samples and their drug sensitivity in the hospital from 2016 to 2020 were retrospectively ana-lyzed.Results A total of 462 strains of pathogenic bacteria were isolated from 5 540 blood culture specimens,including 161 strains of Gram-positive bacteria(34.8％),292 strains of Gram-negative bacteria(63.2％),and 9 strains of fungi(1.9％).The top five pathogens were Escherichia coli 35.7％(165/462),coagulase-negative Staphylococcus 13.4％(62/462),Klebsiella pneumoniae 12.1％(56/462),Staphylococcus aureus 5.6％(26/462)and Enterobacter cloacae 3.0％(14/462).Methicillin-resistant Staphylococcus aureus accounted for 34.6％(9/26)of Staphylococcus aureus,and methicillin-resistant coagulase-negative Staphylococcus accoun-ted for 74.2％(46/62)of coagulase-negative Staphylococcus.Staphylococcus remained sensitive to vancomy-cin,teicoplanin,quinupristin/dalfopristin,tigecycline and linezolid,and no resistant strains were detected.The resistence rates of Escherichia coli and Klebsiella pneumoniae to imipenem were 2.4％and 8.9％respectively.Conclusion There are various kinds of pathogens isolated from blood culture specimens,mainly Gram-nega-tive bacteria.Clinical attention should be paid to blood culture specimens and drug resistance monitoring,ra-tional use of antibiotics,early control of bloodstream infection,reduce the mortality of patients.关键词
血流感染/病原菌/耐药性/耐甲氧西林金黄色葡萄球菌/血培养/感染控制Key words
bloodstream infection/pathogenic bacteria/drug resistance/methicillin-resistant Staphy-lococcus aureus/blood culture/infection control分类
医药卫生引用本文复制引用
严丽,管湘玉..苏州某中医院血流感染病原菌分布及耐药性分析[J].检验医学与临床,2024,21(2):170-173,4.基金项目
张家港市中医医院2019年度青年自然科学基金项目(zzyq1913). （zzyq1913）
