检验医学与临床2024，Vol.21Issue(2)：196-198,3.DOI:10.3969/j.issn.1672-9455.2024.02.012
旴江谢氏刺营疗法配合丹参黏膜下注射治疗口腔黏膜下纤维化的临床研究
Clinical study of acupuncture therapy of Xie's family in Xujiang combined with salvia miltiorrhiza submucosal injection in the treatment of oral submucosal fibrosis
摘要
Abstract
Objective To investigate the effect of acupuncture therapy of Xie's family in Xujiang combined with Salvia miltiorrhiza injection on oral submucosal fibrosis(OSF).Methods A total of 80 patients with OSF admitted to the hospital from January 2020 to June 2022 were selected as the research objects,and they were divided into observation group and control group,with 40 cases in each group.The control group was treated with salvia miltiorrhiza submucosal injection,and the observation group was treated with acupuncture therapy of Xie's family in Xujiang and salvia miltiorrhiza submucosal injection.Both groups were treated for 3 months.The therapeutic effects,symptoms and signs,and serum indexes were compared between the two groups.Results The total effective rate of observation group(95.00％)was higher than that of control group(80.00％),the difference was statistically significant(P＜0.05).After treatment,the visual analogue scale score,mouth opening degree and oral mucosal lesion area of the two groups were all improved compared with those before treatment,and the improvement in the observation group was more significant than that in the control group,the differences were statistically significant(P＜0.05).After treatment,the levels of serum transforming growth factor-β1(TGF-β1)and interleukin-6(IL-6)in the two groups were lower than those be-fore treatment,and those in the observation group were lower than those in the control group,and the differ-ences were statistically significant(P＜0.05).Conclusion The combination therapy of acupuncture therapy of Xie's family in Xujiang and salvia miltiorrhiza submucosal injection is effective in the treatment of OSF,which can effectively improve the clinical symptoms and regulate the serum levels of TGF-β1 and IL-6.关键词
口腔黏膜下纤维化/丹参注射液/吁江谢氏刺营疗法/临床研究/治疗效果Key words
oral submucosal fibrosis/salvia miltiorrhiza injection/acupuncture therapy of Xie's family in Xujiang/clinical research/treatment effect分类
口腔医学引用本文复制引用
黄毅,平江涛,张娟..旴江谢氏刺营疗法配合丹参黏膜下注射治疗口腔黏膜下纤维化的临床研究[J].检验医学与临床,2024,21(2):196-198,3.基金项目
江西省卫生健康委科技计划项目(202311806). （202311806）
