环境与职业医学2024，Vol.41Issue(1)：70-76,7.DOI:10.11836/JEOM23218
孕期大气污染暴露与儿童肥胖风险关系的系统综述
A systemic review on association between on maternal atmospheric pollution exposure during pregnancy and childhood obesity
摘要
Abstract
[Background]Maternal atmospheric pollution during pregnancy may alter fetal intrauterine de-velopment programming,thereby increasing the risk of childhood obesity in the future. [Objective]To investigate the effects of atmospheric pollution exposure during pregnancy on the incidence of childhood obesity in offspring. [Methods]English databases(PubMed,Web of Science,and Medline)and Chinese databases(Wanfang Data Knowledge Service Platform,China National Knowledge Infrastructure,and VIP Information Chinese Journal Service Platform)were searched for literature reporting exposure to atmospheric pollution during pregnancy and childhood obesity published from 1 January 2000 to 31 August 2023.The quality of the included literature was evaluated using the quality assess-ment tools for observational cohort and cross-sectional studies recommended by the US National Institutes of Health. [Results]Twenty-four studies meeting the inclusion criteria were identified and the associated atmospheric pollutants included particulate matter,ozone,nitrogen oxide,carbon oxide,and sulfur oxide.In comparison to the non-exposed group,prenatal exposure to various common at-mospheric pollutants were significantly associated with an elevated risk of childhood obesity in offspring. [Conclusion]Maternal exposure to atmospheric pollution during pregnancy is associated with an elevated risk of childhood obesity in subsequent years.Future studies should pay more attention to the effects of atmospheric pollution on the distribution of children's body fat and metabolic development,and further identify potential mechanisms of atmospheric pollutant exposure leading to childhood obesity.关键词
大气污染/儿童肥胖/孕期/宫内暴露Key words
atmospheric pollution/childhood obesity/pregnancy/intrauterine exposure分类
医药卫生引用本文复制引用
郑璐,刘博蕊,万宁钰,王小川,杨喆,胡嘉晋..孕期大气污染暴露与儿童肥胖风险关系的系统综述[J].环境与职业医学,2024,41(1):70-76,7.基金项目
国家自然科学基金项目(82103860) This study was funded. （82103860）
