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肥胖与银屑病关系的研究进展

聂君儿 欧阳东成 谢琴 杨细飞

皮肤性病诊疗学杂志2024,Vol.31Issue(1):60-66,7.
皮肤性病诊疗学杂志2024,Vol.31Issue(1):60-66,7.DOI:10.3969/j.issn.1674-8468.2024.01.011

肥胖与银屑病关系的研究进展

Research progress in the relationship between obesity and psoriasis

聂君儿 1欧阳东成 2谢琴 3杨细飞4

作者信息

  • 1. 南方医科大学公共卫生学院,广东 广州 510515||广东岭南职业技术学院,广东 广州 510640
  • 2. 广州华夏职业学院,广东 广州 510935
  • 3. 广东岭南职业技术学院,广东 广州 510640
  • 4. 南方医科大学公共卫生学院,广东 广州 510515||深圳市疾病预防控制中心深圳市现代毒理学重点实验室,深圳市卫生毒理学医学重点学科,广东 深圳 518020
  • 折叠

摘要

Abstract

Obesity is a major public health problem worldwide,which is linked to the develop-ment of chronic inflammation and its related complications,such as psoriasis,type 2 diabetes,hy-perlipidemia,atherosclerosis,etc.Obesity and psoriasis can be influenced by multiple factors,such as dietary habits,immune factors,microbiota and environmental factors,but the specific mechanisms are not yet clear.The link between obesity and psoriasis is mainly mediated by fat factors in obese and psoriatic patients,which can activate pro-inflammatory factors,thereby exac-erbating psoriasis symptoms.Obesity is one of the important risk factors for psoriatic patients.And compared to normal weight individuals,overweight or obesity can worsen psoriasis.This paper re-views the possible connections between obesity and psoriasis from multiple aspects,including epi-demiology,anthropometric indicators,microbiota,diet,pro-inflammatory factors and treatment.

关键词

肥胖/银屑病/人体测量指标/微生物群/饮食/促炎因子/治疗

Key words

obesity/psoriasis/anthropometric indicators/microbial community/diet/pro-inflammatory factors/treatment

引用本文复制引用

聂君儿,欧阳东成,谢琴,杨细飞..肥胖与银屑病关系的研究进展[J].皮肤性病诊疗学杂志,2024,31(1):60-66,7.

基金项目

国家自然科学基金(82171583) (82171583)

深圳市基础研究重点项目(JCYJ20200109150717745) (JCYJ20200109150717745)

皮肤性病诊疗学杂志

1674-8468

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