生命科学仪器2023，Vol.21Issue(5)：8-14,7.DOI:10.11967/2023211002
环化核苷酸的功能研究进展
Research Progress on the Function of Cyclic Nucleotides
摘要
Abstract
Cyclic nucleotides are cyclic diester small molecules formed by one or more nucleotide monophosphates through phosphodiester bonds.As signal transduction molecule,they play important roles in many physiological functions including cell metabolism,transcription regulation and cell growth.The latest research has found that va-rious types of cyclic nucleotide molecules can activate the innate immune response of metazoans and the anti-phage defense system of bacteria.This article summarizes the types of cyclic nucleotides discovered so far,briefly reviews the research progress of their functional mechanisms,and puts forward the current problems and potential develop-ment directions.关键词
环化核苷酸/信号通路调控/固有免疫/适应性进化Key words
cyclic nucleotides/regulation of signal pathway/innate immunity/adaptive evolution分类
生物科学引用本文复制引用
李钊,高昂..环化核苷酸的功能研究进展[J].生命科学仪器,2023,21(5):8-14,7.基金项目
国家自然科学基金项目(32171219) （32171219）
