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太空失重肌萎缩及药物防护研究进展

武睿鹏 张瀚文 刘秀云 李玉娟

生命科学仪器2023,Vol.21Issue(5):15-21,7.
生命科学仪器2023,Vol.21Issue(5):15-21,7.DOI:10.11967/2023211003

太空失重肌萎缩及药物防护研究进展

ResearchProgress of Muscle Atrophy and Drug Protection in Weightlessness in Space

武睿鹏 1张瀚文 1刘秀云 2李玉娟1

作者信息

  • 1. 北京理工大学生命学院,北京 100081
  • 2. 解放军总医院京北医疗区北清路门诊部,北京 100094
  • 折叠

摘要

Abstract

Microgravity,strong radiation,noise and other environmental factors in space could cause different de-grees of physiological and pathological damage to astronauts.In order to ensure the physical and mental health of astronauts and the smooth development of space work,it is very important to study the mechanism of physiological and pathological damage and corresponding drug protection in space environment.Skeletal muscle atrophy and muscle strength decline caused by weightlessness are relatively significant,however the mechanism of the weight-less atrophy is still unclear and there is a lack of drug intervention.In this paper,the mechanism of muscle atrophy under current weightlessness and simulated weightlessness as well as related protective drugs will be reviewed,so as to provide research basis for the protection of muscle atrophy caused by weightlessness,or provide reference for the research of protective drugs for muscle atrophy under weightlessness.

关键词

失重/肌萎缩/药物防护

Key words

Weightlessness/Muscular atrophy/Drug protection

分类

医药卫生

引用本文复制引用

武睿鹏,张瀚文,刘秀云,李玉娟..太空失重肌萎缩及药物防护研究进展[J].生命科学仪器,2023,21(5):15-21,7.

基金项目

航天员健康中心重点实验室研究基金(AHCC2021KF004) (AHCC2021KF004)

生命科学仪器

1671-7929

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