畜牧兽医学报2024，Vol.55Issue(1)：59-70,12.DOI:10.11843/j.issn.0366-6964.2024.01.007
病毒感染与宿主抗感染免疫之间"博弈"——凋亡、坏死和焦亡分子机制
Molecular Mechanism of the"Battle"between Virus Infection and Host Antiviral Immunity-Apoptosis,Necroptosis and Pyroptosis
摘要
Abstract
Cell death is an important component of host antiviral immunity response,viral infection can cause different forms of host cell death,including the lytic and non-lytic cell death mode.These types of cell death not only eliminate virus-infected cells,but also further promote the host's innate and adaptive immune processes through release of inflammatory factors.On the contrary,viruses have developed different circumvention mechanisms to inhibit cell death and promote itself infection.This review summarized the research progress in the regulation mechanism of virus-host infection and anti-infection immunity struggle-apoptosis,necroptosis and pyroptosis,aiming to provide references for further understanding the viral molecules pathogenesis and developing a new antiviral strategy.关键词
病毒/宿主/博弈/凋亡/坏死/焦亡Key words
viruses/host/struggle/apoptosis/necroptosis/pyroptosis分类
农业科技引用本文复制引用
陈松彪,丁轲,刘飞飞,尚珂,余祖华,何雷,魏颖,陈建,张春杰,程相朝..病毒感染与宿主抗感染免疫之间"博弈"——凋亡、坏死和焦亡分子机制[J].畜牧兽医学报,2024,55(1):59-70,12.基金项目
河南省科技研发计划联合基金资助项目(232103810029) （232103810029）
河南省自然科学基金资助项目(232300421263) （232300421263）
河南科技大学博士启动基金资助项目(13480104) （13480104）
